A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of MHAA4549A, a Monoclonal Antibody, plus Oseltamivir in Patients Hospitalized with Severe Influenza A Virus Infection

For patients hospitalized with severe influenza A virus infection, morbidity and mortality remain high. MHAA4549A, a human monoclonal antibody targeting the influenza A virus hemagglutinin stalk, has demonstrated pharmacological activity in animal studies and in a human influenza A challenge study....

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Detalles Bibliográficos
Autores principales: Lim, Jeremy J., Nilsson, Anna C., Silverman, Michael, Assy, Nimer, Kulkarni, Priya, McBride, Jacqueline M., Deng, Rong, Li, Chloe, Yang, Xiaoying, Nguyen, Allen, Horn, Priscilla, Maia, Mauricio, Castro, Aide, Peck, Melicent C., Galanter, Joshua, Chu, Tom, Newton, Elizabeth M., Tavel, Jorge A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318030/
https://www.ncbi.nlm.nih.gov/pubmed/32393496
http://dx.doi.org/10.1128/AAC.00352-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318030/
https://www.ncbi.nlm.nih.gov/pubmed/32393496
http://dx.doi.org/10.1128/AAC.00352-20

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