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Synthesis, Stability, and Biological Studies of Fluorinated Analogues of Thromboxane A(2)

[Image: see text] Platelet activation results in the generation of thromboxane A(2) (TxA(2)), which promotes thrombus formation by further amplifying platelet function, as well as causing vasoconstriction. Due to its role in thrombus formation and cardiovascular disease, its production is the target...

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Detalles Bibliográficos
Autores principales: Jing, Changcheng, Mallah, Shahida, Kriemen, Ella, Bennett, Steven H., Fasano, Valerio, Lennox, Alastair J. J., Hers, Ingeborg, Aggarwal, Varinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318075/
https://www.ncbi.nlm.nih.gov/pubmed/32607446
http://dx.doi.org/10.1021/acscentsci.0c00310