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Transmission of CJD from nasal brushings but not spinal fluid or RT‐QuIC product

OBJECTIVE: The detection of prion seeding activity in CSF and olfactory mucosal brushings using real‐time quaking‐induced conversion assays allows highly accurate clinical diagnosis of sporadic Creutzfeldt–Jakob disease. To gauge transmission risks associated with these biospecimens and their testin...

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Detalles Bibliográficos
Autores principales: Raymond, Gregory J., Race, Brent, Orrú, Christina D., Raymond, Lynne D., Bongianni, Matilde, Fiorini, Michele, Groveman, Bradley R., Ferrari, Sergio, Sacchetto, Luca, Hughson, Andrew G., Monaco, Salvatore, Pocchiari, Maurizio, Zanusso, Gianluigi, Caughey, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318090/
https://www.ncbi.nlm.nih.gov/pubmed/32538552
http://dx.doi.org/10.1002/acn3.51057