Evaluation of hydrophobic‐interaction chromatography resins for purification of antibody‐drug conjugates using a mimetic model with adjustable hydrophobicity

Antibody drug conjugates are cytotoxic pharmaceuticals, designed to destroy malignant cells. A cytotoxic molecule is attached to an antibody that binds specific to a cancer‐cell surface. Given the high toxicity of the drugs, strict safety standards have to be kept. For this reason, an antibody drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Egbert, Sevilla, Manuela, Endres, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Liquid Chromatography
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318155/
https://www.ncbi.nlm.nih.gov/pubmed/32160397
http://dx.doi.org/10.1002/jssc.201900895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318155/
https://www.ncbi.nlm.nih.gov/pubmed/32160397
http://dx.doi.org/10.1002/jssc.201900895

Ejemplares similares