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Nonclinical safety assessment of repeated administration and biodistribution of ChAd3‐EBO‐Z Ebola candidate vaccine

ChAd3‐EBO‐Z is an investigational adenovirus‐based vaccine for the prevention of Ebola virus disease. Two nonclinical studies were performed to evaluate the biodistribution, local tolerance and potential local and systemic toxic effects of this vaccine. In the biodistribution study, rats received a...

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Detalles Bibliográficos
Autores principales: Planty, Camille, Chevalier, Guillaume, Duclos, Marie‐Ève, Chalmey, Clémentine, Thirion‐Delalande, Catherine, Sobry, Cécile, Steff, Ann‐Muriel, Destexhe, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318182/
https://www.ncbi.nlm.nih.gov/pubmed/31965598
http://dx.doi.org/10.1002/jat.3941