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Nonclinical safety assessment of repeated administration and biodistribution of ChAd3‐EBO‐Z Ebola candidate vaccine
ChAd3‐EBO‐Z is an investigational adenovirus‐based vaccine for the prevention of Ebola virus disease. Two nonclinical studies were performed to evaluate the biodistribution, local tolerance and potential local and systemic toxic effects of this vaccine. In the biodistribution study, rats received a...
Autores principales: | Planty, Camille, Chevalier, Guillaume, Duclos, Marie‐Ève, Chalmey, Clémentine, Thirion‐Delalande, Catherine, Sobry, Cécile, Steff, Ann‐Muriel, Destexhe, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318182/ https://www.ncbi.nlm.nih.gov/pubmed/31965598 http://dx.doi.org/10.1002/jat.3941 |
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