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Comparing the Pharmacokinetics of 2 Novel Intravenous Tramadol Dosing Regimens to Oral Tramadol: A Randomized 3‐Arm Crossover Study

Tramadol is a dual‐mechanism (opiate and monoamine reuptake inhibition) analgesic. Intravenous (IV) tramadol has been widely prescribed outside the United States. However, there have not been studies comparing the pharmacokinetics (PK) of IV dosing regimens to that of oral tramadol. In this phase 1,...

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Detalles Bibliográficos
Autores principales: Lu, Lucy, Ryan, Michael, Harnett, Mark, Atiee, George J., Reines, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318183/
https://www.ncbi.nlm.nih.gov/pubmed/31610100
http://dx.doi.org/10.1002/cpdd.746