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Association of increased hepatic insulin clearance and change in serum triglycerides or β‐hydroxybutyrate concentration via the sodium/glucose‐cotransporter 2 inhibitor tofogliflozin

AIMS: Obesity and hepatic fat accumulation diminish hepatic insulin clearance, which can cause hyperinsulinaemia. Sodium/glucose‐cotransporter 2 inhibitors (SGLT2‐is) improve insulin resistance and hyperinsulinaemia by weight loss via increased urinary glucose excretion in type 2 diabetes. However,...

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Detalles Bibliográficos
Autores principales: Matsubayashi, Yasuhiro, Yoshida, Akihiro, Suganami, Hideki, Osawa, Taeko, Furukawa, Kazuo, Suzuki, Hiroshi, Fujihara, Kazuya, Tanaka, Shiro, Kaku, Kohei, Sone, Hirohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318197/
https://www.ncbi.nlm.nih.gov/pubmed/31984623
http://dx.doi.org/10.1111/dom.13980