A Focus on Unusual ECL2 Interactions Yields β(2)‐Adrenergic Receptor Antagonists with Unprecedented Scaffolds

The binding pockets of aminergic G protein‐coupled receptors are often targeted by drugs and virtual screening campaigns. In order to find ligands with unprecedented scaffolds for one of the best‐investigated receptors of this subfamily, the β(2)‐adrenergic receptor, we conducted a docking‐based scr...

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Detalles Bibliográficos
Autores principales: Scharf, Magdalena M., Zimmermann, Mirjam, Wilhelm, Florian, Stroe, Raimond, Waldhoer, Maria, Kolb, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318225/
https://www.ncbi.nlm.nih.gov/pubmed/32301583
http://dx.doi.org/10.1002/cmdc.201900715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318225/
https://www.ncbi.nlm.nih.gov/pubmed/32301583
http://dx.doi.org/10.1002/cmdc.201900715

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