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A Focus on Unusual ECL2 Interactions Yields β(2)‐Adrenergic Receptor Antagonists with Unprecedented Scaffolds
The binding pockets of aminergic G protein‐coupled receptors are often targeted by drugs and virtual screening campaigns. In order to find ligands with unprecedented scaffolds for one of the best‐investigated receptors of this subfamily, the β(2)‐adrenergic receptor, we conducted a docking‐based scr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318225/ https://www.ncbi.nlm.nih.gov/pubmed/32301583 http://dx.doi.org/10.1002/cmdc.201900715 |