Genome‐wide characterization of 5‐hydoxymethylcytosine in melanoma reveals major differences with nevus

Melanoma demonstrates altered patterns of DNA methylation that are associated with genetic instability and transcriptional repression of numerous genes. Active DNA demethylation is mediated by TET enzymes that catalyze conversion of 5‐methylcytosine (mC) to 5‐hydroxymethylcytosine (hmC). Loss of hmC...

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Detalles Bibliográficos
Autores principales: Salgado, Catarina, Oosting, Jan, Janssen, Bart, Kumar, Rajiv, Gruis, Nelleke, van Doorn, Remco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318264/
https://www.ncbi.nlm.nih.gov/pubmed/32017278
http://dx.doi.org/10.1002/gcc.22837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318264/
https://www.ncbi.nlm.nih.gov/pubmed/32017278
http://dx.doi.org/10.1002/gcc.22837

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