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Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis

AIMS: Clusterin is a topologically dynamic chaperone protein with the ability to participate in both intra‐ and extacellular proteostasis. Clusterin has been shown to be upregulated in the spinal cord of patients with amyotrophic lateral sclerosis (ALS) and has been shown to protect against TDP‐43 p...

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Detalles Bibliográficos
Autores principales: Gregory, J. M., Elliott, E., McDade, K., Bak, T., Pal, S., Chandran, S., Abrahams, S., Smith, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318312/
https://www.ncbi.nlm.nih.gov/pubmed/31386770
http://dx.doi.org/10.1111/nan.12575