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Structure Validation of G‐Rich RNAs in Noncoding Regions of the Human Genome

We present the rapid biophysical characterization of six previously reported putative G‐quadruplex‐forming RNAs from the 5′‐untranslated region (5′‐UTR) of silvestrol‐sensitive transcripts for investigation of their secondary structures. By NMR and CD spectroscopic analysis, we found that only a sin...

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Detalles Bibliográficos
Autores principales: Binas, Oliver, Bessi, Irene, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318348/
https://www.ncbi.nlm.nih.gov/pubmed/31943589
http://dx.doi.org/10.1002/cbic.201900696