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Inhibition of Notch pathway enhances the anti-tumor effect of docetaxel in prostate cancer stem-like cells

BACKGROUND: Prostate cancer stem-like cells (PCSCs) likely participate in tumor progression and recurrence and demonstrate resistance to chemotherapy. The Notch pathway plays a role in the maintenance of the stemness in PCSCs. This study aimed to investigate the efficacy of Notch signaling inhibitio...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Zi, Hao, Luo, Yi, Liu, Tongzu, Zheng, Hang, Xie, Conghua, Wang, Xinghuan, Huang, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318403/
https://www.ncbi.nlm.nih.gov/pubmed/32586404
http://dx.doi.org/10.1186/s13287-020-01773-w