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Inhibition of Notch pathway enhances the anti-tumor effect of docetaxel in prostate cancer stem-like cells
BACKGROUND: Prostate cancer stem-like cells (PCSCs) likely participate in tumor progression and recurrence and demonstrate resistance to chemotherapy. The Notch pathway plays a role in the maintenance of the stemness in PCSCs. This study aimed to investigate the efficacy of Notch signaling inhibitio...
Autores principales: | Wang, Lei, Zi, Hao, Luo, Yi, Liu, Tongzu, Zheng, Hang, Xie, Conghua, Wang, Xinghuan, Huang, Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318403/ https://www.ncbi.nlm.nih.gov/pubmed/32586404 http://dx.doi.org/10.1186/s13287-020-01773-w |
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