Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model

BACKGROUND: Extracellular vesicles produced by bone marrow mesenchymal stem cells (BMSC-EVs) can play important roles in the repair of injured tissues. Though numerous studies have reported the effect of EVs on renal fibrosis, the underlying mechanisms remain unclear. We hypothesized that BMSC-EVs c...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Zhengzhou, Wang, Qi, Zhang, Youbo, Jiang, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318505/
https://www.ncbi.nlm.nih.gov/pubmed/32586368
http://dx.doi.org/10.1186/s13287-020-01767-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318505/
https://www.ncbi.nlm.nih.gov/pubmed/32586368
http://dx.doi.org/10.1186/s13287-020-01767-8

Ejemplares similares