Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription

8‐Oxoguanine DNA glycosylase1 (OGG1)‐initiated base excision repair (BER) is the primary pathway to remove the pre‐mutagenic 8‐oxo‐7,8‐dihydroguanine (8‐oxoG) from DNA. Recent studies documented 8‐oxoG serves as an epigenetic‐like mark and OGG1 modulates gene expression in oxidatively stressed cells...

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Detalles Bibliográficos
Autores principales: Hao, Wenjing, Wang, Jing, Zhang, Yuanhang, Wang, Chenxin, Xia, Lan, Zhang, Wenhe, Zafar, Muhammad, Kang, Ju‐Yong, Wang, Ruoxi, Ali Bohio, Ameer, Pan, Lang, Zeng, Xianlu, Wei, Min, Boldogh, Istvan, Ba, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318607/
https://www.ncbi.nlm.nih.gov/pubmed/32378256
http://dx.doi.org/10.1096/fj.201902243R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318607/
https://www.ncbi.nlm.nih.gov/pubmed/32378256
http://dx.doi.org/10.1096/fj.201902243R

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