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Modeling early stages of endoderm development in epiblast stem cell aggregates with supply of extracellular matrices

Endoderm precursors expressing FoxA2 and Sox17 develop from the epiblast through the gastrulation process. In this study, we developed an experimental system to model the endoderm‐generating gastrulation process using epiblast stem cells (EpiSCs). To this end, we established an EpiSC line i22, in wh...

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Detalles Bibliográficos
Autores principales: Inamori, Sachiko, Fujii, Mai, Satake, Sayaka, Iida, Hideaki, Teramoto, Machiko, Sumi, Tomoyuki, Meno, Chikara, Ishii, Yasuo, Kondoh, Hisato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318635/
https://www.ncbi.nlm.nih.gov/pubmed/32277710
http://dx.doi.org/10.1111/dgd.12663