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Generation and analysis of novel Reln‐deleted mouse model corresponding to exonic Reln deletion in schizophrenia

AIM: A Japanese individual with schizophrenia harboring a novel exonic deletion in RELN was recently identified by genome‐wide copy‐number variation analysis. Thus, the present study aimed to generate and analyze a model mouse to clarify whether Reln deficiency is associated with the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Sawahata, Masahito, Mori, Daisuke, Arioka, Yuko, Kubo, Hisako, Kushima, Itaru, Kitagawa, Kanako, Sobue, Akira, Shishido, Emiko, Sekiguchi, Mariko, Kodama, Akiko, Ikeda, Ryosuke, Aleksic, Branko, Kimura, Hiroki, Ishizuka, Kanako, Nagai, Taku, Kaibuchi, Kozo, Nabeshima, Toshitaka, Yamada, Kiyofumi, Ozaki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318658/
https://www.ncbi.nlm.nih.gov/pubmed/32065683
http://dx.doi.org/10.1111/pcn.12993