Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase

BACKGROUND: The Src homology region 2 domain-containing phosphatase-1 (SHP-1) is known to exert negative regulatory effects on immune cell signaling. Mice with mutations in the Shp1 gene develop inflammatory skin disease and autoimmunity, but no arthritis. We sought to explore the role of SHP-1 in a...

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Detalles Bibliográficos
Autores principales: Markovics, Adrienn, Toth, Daniel M., Glant, Tibor T., Mikecz, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318740/
https://www.ncbi.nlm.nih.gov/pubmed/32586377
http://dx.doi.org/10.1186/s13075-020-02250-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318740/
https://www.ncbi.nlm.nih.gov/pubmed/32586377
http://dx.doi.org/10.1186/s13075-020-02250-8

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