Shrimp miR-965 induced the human melanoma stem-like cell apoptosis and inhibited their stemness by disrupting the MCL-1-ER stress-XBP1 feedback loop in a cross-species manner

BACKGROUND: Melanoma is a type of aggressive skin cancer with a poor survival rate. The resistance to conventional therapy of this disease is, at least in part, attributed to its cancer stem cell population. However, the mechanism of survival and stemness maintenance of cancer stem cells remains to...

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Detalles Bibliográficos
Autores principales: Wu, Wenlin, Xu, Chenxi, Zhang, Xiaobo, Yu, An, Shu, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318764/
https://www.ncbi.nlm.nih.gov/pubmed/32586376
http://dx.doi.org/10.1186/s13287-020-01734-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318764/
https://www.ncbi.nlm.nih.gov/pubmed/32586376
http://dx.doi.org/10.1186/s13287-020-01734-3

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