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Tiotropium and Fluticasone Inhibit Rhinovirus-Induced Mucin Production via Multiple Mechanisms in Differentiated Airway Epithelial Cells

Human rhinoviruses (HRVs) are associated with acute exacerbations in patients with chronic obstructive pulmonary disease (COPD) and asthma, which are accompanied by mucus hypersecretion. Whereas, various studies have shown that HRVs increase epithelial mucin production and thus may directly contribu...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Ninaber, Dennis K., van Schadewijk, Annemarie, Hiemstra, Pieter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318795/
https://www.ncbi.nlm.nih.gov/pubmed/32637364
http://dx.doi.org/10.3389/fcimb.2020.00278