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Clinical Diagnosis of Red Cell Membrane Disorders: Comparison of Osmotic Gradient Ektacytometry and Eosin Maleimide (EMA) Fluorescence Test for Red Cell Band 3 (AE1, SLC4A1) Content for Clinical Diagnosis

The measurement of band 3 (AE1, SLC4A1, CD233) content of red cells by eosin-5- maleimide (EMA) staining is swiftly replacing conventional osmotic fragility (OF) test as a tool for laboratory confirmation of hereditary spherocytosis across the globe. Our group has systematically evaluated the EMA te...

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Detalles Bibliográficos
Autores principales: Zaidi, Ahmar Urooj, Buck, Steven, Gadgeel, Manisha, Herrera-Martinez, Miguel, Mohan, Araathi, Johnson, Kenya, Bagla, Shruti, Johnson, Robert M., Ravindranath, Yaddanapudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318840/
https://www.ncbi.nlm.nih.gov/pubmed/32636758
http://dx.doi.org/10.3389/fphys.2020.00636