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HMGB1/PI3K/Akt/mTOR Signaling Participates in the Pathological Process of Acute Lung Injury by Regulating the Maturation and Function of Dendritic Cells

Background: High-mobility group box 1 protein (HMGB1) was identified as a highly conserved DNA binding nuclear protein, which participates in the processes of acute lung injury (ALI). HMGB1 binds to its specific receptors not only to activate the nuclear factor (NF)-κB and mitogen-activated protein...

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Detalles Bibliográficos
Autores principales: Li, Ruiting, Zou, Xiaojing, Huang, Haiyan, Yu, Yuan, Zhang, Hongmei, Liu, Pei, Pan, Shangwen, Ouyang, Yaqi, Shang, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318890/
https://www.ncbi.nlm.nih.gov/pubmed/32636835
http://dx.doi.org/10.3389/fimmu.2020.01104