Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain

Despite growing evidence suggesting that spinal microglia play an important role in the molecular mechanism underlying experimental neuropathic pain (NP) in male rodents, evidence regarding the sex-dependent role of these microglia in NP is insufficient. In this study, we evaluated the effects of mi...

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Detalles Bibliográficos
Autores principales: Saika, Fumihiro, Matsuzaki, Shinsuke, Kobayashi, Daichi, Ideguchi, Yuya, Nakamura, Tomoe Y., Kishioka, Shiroh, Kiguchi, Norikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318895/
https://www.ncbi.nlm.nih.gov/pubmed/32636748
http://dx.doi.org/10.3389/fphar.2020.00925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318895/
https://www.ncbi.nlm.nih.gov/pubmed/32636748
http://dx.doi.org/10.3389/fphar.2020.00925

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