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An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila

Circular RNAs (circRNAs) are abundant and accumulate with age in neurons of diverse species. However, only few circRNAs have been functionally characterized, and their role during aging has not been addressed. Here, we use transcriptome profiling during aging and find that accumulation of circRNAs i...

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Detalles Bibliográficos
Autores principales: Weigelt, Carina Marianne, Sehgal, Rohan, Tain, Luke Stephen, Cheng, Jun, Eßer, Jacqueline, Pahl, André, Dieterich, Christoph, Grönke, Sebastian, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318944/
https://www.ncbi.nlm.nih.gov/pubmed/32592682
http://dx.doi.org/10.1016/j.molcel.2020.06.011