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Effect of ciclosporin on safety, lymphocyte kinetics and left ventricular remodelling in acute myocardial infarction

AIMS: Following a favourable pilot trial using a single bolus of ciclosporin, it has been unclear why 2 large studies (CYCLE and CIRCUS) failed to prevent reperfusion injury and reduce infarct size in STEMI (ST elevation myocardial infarction). The purpose of this study was to assess the effect of c...

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Detalles Bibliográficos
Autores principales: Cormack, Suzanne, Mohammed, Ashfaq, Panahi, Pedram, Das, Rajiv, Steel, Alison J., Chadwick, Thomas, Bryant, Andrew, Egred, Mohaned, Stellos, Konstantinos, Spyridopoulos, Ioakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318996/
https://www.ncbi.nlm.nih.gov/pubmed/32067256
http://dx.doi.org/10.1111/bcp.14252