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Successes and Failures of the Live-attenuated Influenza Vaccine: Can We Do Better?

BACKGROUND: The effectiveness of the live-attenuated influenza vaccine (LAIV) can vary widely, ranging from 0% to 50%. The reasons for these discrepancies remain largely unclear. METHODS: We use mathematical models to explore how the efficacy of LAIV is affected by the degree of mismatch with the cu...

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Detalles Bibliográficos
Autores principales: Matrajt, Laura, Halloran, M Elizabeth, Antia, Rustom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319054/
https://www.ncbi.nlm.nih.gov/pubmed/31056675
http://dx.doi.org/10.1093/cid/ciz358