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Successes and Failures of the Live-attenuated Influenza Vaccine: Can We Do Better?
BACKGROUND: The effectiveness of the live-attenuated influenza vaccine (LAIV) can vary widely, ranging from 0% to 50%. The reasons for these discrepancies remain largely unclear. METHODS: We use mathematical models to explore how the efficacy of LAIV is affected by the degree of mismatch with the cu...
Autores principales: | Matrajt, Laura, Halloran, M Elizabeth, Antia, Rustom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319054/ https://www.ncbi.nlm.nih.gov/pubmed/31056675 http://dx.doi.org/10.1093/cid/ciz358 |
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