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A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2

Developing therapeutics against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be guided by the distribution of epitopes, not only on the receptor binding domain (RBD) of the Spike (S) protein but also across the full Spike (S) protein. We isolated and characterized monoclonal an...

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Detalles Bibliográficos
Autores principales: Chi, Xiangyang, Yan, Renhong, Zhang, Jun, Zhang, Guanying, Zhang, Yuanyuan, Hao, Meng, Zhang, Zhe, Fan, Pengfei, Dong, Yunzhu, Yang, Yilong, Chen, Zhengshan, Guo, Yingying, Zhang, Jinlong, Li, Yaning, Song, Xiaohong, Chen, Yi, Xia, Lu, Fu, Ling, Hou, Lihua, Xu, Junjie, Yu, Changming, Li, Jianmin, Zhou, Qiang, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319273/
https://www.ncbi.nlm.nih.gov/pubmed/32571838
http://dx.doi.org/10.1126/science.abc6952