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A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics
The transcription factors NF-κB and p53 are key regulators in the genotoxic stress response and are critical for tumor development. Although there is ample evidence for interactions between both networks, a comprehensive understanding of the crosstalk is lacking. Here, we developed a systematic appr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319280/ https://www.ncbi.nlm.nih.gov/pubmed/32589666 http://dx.doi.org/10.1371/journal.pcbi.1007901 |