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p120-catenin phosphorylation status alters E-cadherin mediated cell adhesion and ability of tumor cells to metastasize

p120-catenin is considered to be a tumor suppressor because it stabilizes E-cadherin levels at the cell surface. p120-catenin phosphorylation is increased in several types of cancer, but the role of phosphorylation in cancer is unknown. The phosphorylation state of p120-catenin is important in contr...

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Detalles Bibliográficos
Autores principales: Mendonsa, Alisha M., Bandyopadhyay, Chirosree, Gumbiner, Barry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319294/
https://www.ncbi.nlm.nih.gov/pubmed/32589661
http://dx.doi.org/10.1371/journal.pone.0235337