Restriction of S-adenosylmethionine conformational freedom by knotted protein binding sites

S-adenosylmethionine (SAM) is one of the most important enzyme substrates. It is vital for the function of various proteins, including large group of methyltransferases (MTs). Intriguingly, some bacterial and eukaryotic MTs, while catalysing the same reaction, possess significantly different topolog...

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Detalles Bibliográficos
Autores principales: Perlinska, Agata P., Stasiulewicz, Adam, Nawrocka, Ewa K., Kazimierczuk, Krzysztof, Setny, Piotr, Sulkowska, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319350/
https://www.ncbi.nlm.nih.gov/pubmed/32453784
http://dx.doi.org/10.1371/journal.pcbi.1007904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319350/
https://www.ncbi.nlm.nih.gov/pubmed/32453784
http://dx.doi.org/10.1371/journal.pcbi.1007904

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