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SPEED2: inferring upstream pathway activity from differential gene expression
Extracting signalling pathway activities from transcriptome data is important to infer mechanistic origins of transcriptomic dysregulation, for example in disease. A popular method to do so is by enrichment analysis of signature genes in e.g. differentially regulated genes. Previously, we derived si...
Autores principales: | Rydenfelt, Mattias, Klinger, Bertram, Klünemann, Martina, Blüthgen, Nils |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319438/ https://www.ncbi.nlm.nih.gov/pubmed/32313938 http://dx.doi.org/10.1093/nar/gkaa236 |
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