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Prediction of synonymous corrections by the BE-FF computational tool expands the targeting scope of base editing
Base editing is a genome-editing approach that employs the CRISPR/Cas system to precisely install point mutations within the genome. A deaminase enzyme is fused to a deactivated Cas and enables transition conversions. The diversified repertoire of base editors provides a wide range of base editing p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319459/ https://www.ncbi.nlm.nih.gov/pubmed/32255179 http://dx.doi.org/10.1093/nar/gkaa215 |