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AlloSigMA 2: paving the way to designing allosteric effectors and to exploring allosteric effects of mutations

The AlloSigMA 2 server provides an interactive platform for exploring the allosteric signaling caused by ligand binding and/or mutations, for analyzing the allosteric effects of mutations and for detecting potential cancer drivers and pathogenic nsSNPs. It can also be used for searching latent allos...

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Detalles Bibliográficos
Autores principales: Tan, Zhen Wah, Guarnera, Enrico, Tee, Wei-Ven, Berezovsky, Igor N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319554/
https://www.ncbi.nlm.nih.gov/pubmed/32392302
http://dx.doi.org/10.1093/nar/gkaa338