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AlloSigMA 2: paving the way to designing allosteric effectors and to exploring allosteric effects of mutations
The AlloSigMA 2 server provides an interactive platform for exploring the allosteric signaling caused by ligand binding and/or mutations, for analyzing the allosteric effects of mutations and for detecting potential cancer drivers and pathogenic nsSNPs. It can also be used for searching latent allos...
Autores principales: | Tan, Zhen Wah, Guarnera, Enrico, Tee, Wei-Ven, Berezovsky, Igor N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319554/ https://www.ncbi.nlm.nih.gov/pubmed/32392302 http://dx.doi.org/10.1093/nar/gkaa338 |
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