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mCSM-membrane: predicting the effects of mutations on transmembrane proteins

Significant efforts have been invested into understanding and predicting the molecular consequences of mutations in protein coding regions, however nearly all approaches have been developed using globular, soluble proteins. These methods have been shown to poorly translate to studying the effects of...

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Detalles Bibliográficos
Autores principales: Pires, Douglas E V, Rodrigues, Carlos H M, Ascher, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319563/
https://www.ncbi.nlm.nih.gov/pubmed/32469063
http://dx.doi.org/10.1093/nar/gkaa416