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mmCSM-AB: guiding rational antibody engineering through multiple point mutations
While antibodies are becoming an increasingly important therapeutic class, especially in personalized medicine, their development and optimization has been largely through experimental exploration. While there have been many efforts to develop computational tools to guide rational antibody engineeri...
Autores principales: | Myung, Yoochan, Pires, Douglas E V, Ascher, David B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319589/ https://www.ncbi.nlm.nih.gov/pubmed/32432715 http://dx.doi.org/10.1093/nar/gkaa389 |
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