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Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections
Ebselen is an organoselenium compound exhibiting hydroperoxide- and peroxynitrite-reducing activity, acting as a glutathione peroxidase and peroxiredoxin enzyme mimetic. Ebselen reacts with a multitude of protein thiols, forming a selenosulfide bond, which results in pleiotropic effects of antiviral...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319625/ https://www.ncbi.nlm.nih.gov/pubmed/32598985 http://dx.doi.org/10.1016/j.freeradbiomed.2020.06.032 |