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Drug repurposing: Discovery of troxipide analogs as potent antitumor agents

Drug repurposing plays a vital role in the discovery of undescribed bioactivities in clinical drugs. Based on drug repurposing strategy, we for the first time reported a novel series of troxipide analogs and then evaluated their antiproliferative activity against MCF-7, PC3, MGC-803, and PC9 cancer...

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Detalles Bibliográficos
Autores principales: Lu, Nan, Huo, Jin-ling, Wang, Shuai, Yuan, Xiao-Han, Liu, Hong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319647/
https://www.ncbi.nlm.nih.gov/pubmed/32619887
http://dx.doi.org/10.1016/j.ejmech.2020.112471