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Label-free sensing of exosomal MCT1 and CD147 for tracking metabolic reprogramming and malignant progression in glioma

Malignant glioma is a fatal brain tumor whose pathological progression is closely associated with glycolytic reprogramming, leading to the high expression of monocarboxylate transporter 1 (MCT1) and its ancillary protein, cluster of differentiation 147 (CD147) for enhancing lactate efflux. In partic...

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Detalles Bibliográficos
Autores principales: Thakur, A., Qiu, G., Xu, C., Han, X., Yang, T., NG, S. P., Chan, K. W. Y., Wu, C. M. L., Lee, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319757/
https://www.ncbi.nlm.nih.gov/pubmed/32637597
http://dx.doi.org/10.1126/sciadv.aaz6119