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Label-free sensing of exosomal MCT1 and CD147 for tracking metabolic reprogramming and malignant progression in glioma
Malignant glioma is a fatal brain tumor whose pathological progression is closely associated with glycolytic reprogramming, leading to the high expression of monocarboxylate transporter 1 (MCT1) and its ancillary protein, cluster of differentiation 147 (CD147) for enhancing lactate efflux. In partic...
Autores principales: | Thakur, A., Qiu, G., Xu, C., Han, X., Yang, T., NG, S. P., Chan, K. W. Y., Wu, C. M. L., Lee, Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319757/ https://www.ncbi.nlm.nih.gov/pubmed/32637597 http://dx.doi.org/10.1126/sciadv.aaz6119 |
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