SOD3 induces a HIF-2α-dependent program in endothelial cells that provides a selective signal for tumor infiltration by T cells

BACKGROUND: Tumor-infiltrating lymphocytes (TILs), mainly CD8(+) cytotoxic T lymphocytes (CTL), are linked to immune-mediated control of human cancers and response to immunotherapy. Tumors have nonetheless developed specific mechanisms that selectively restrict T cell entry into the tumor microenvir...

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Detalles Bibliográficos
Autores principales: Carmona-Rodríguez, Lorena, Martínez-Rey, Diego, Fernández-Aceñero, Maria Jesús, González-Martín, Alicia, Paz-Cabezas, Mateo, Rodríguez-Rodríguez, Noe, Pérez-Villamil, Beatriz, Sáez, Maria Eugenia, Díaz-Rubio, Eduardo, Mira, Emilia, Mañes, Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319787/
https://www.ncbi.nlm.nih.gov/pubmed/32591431
http://dx.doi.org/10.1136/jitc-2019-000432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319787/
https://www.ncbi.nlm.nih.gov/pubmed/32591431
http://dx.doi.org/10.1136/jitc-2019-000432

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