Inhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib

INTRODUCTION: Skp2 is an E3 ubiquitin ligase that plays an important role in modulating tumor progression. The mechanisms underlying Skp2 in the promotion of proliferation and its function in the primary resistance to tyrosine kinase inhibitors (TKIs) in human CML remain to be determined. This study...

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Detalles Bibliográficos
Autores principales: Chen, Xiaowen, Huang, Zhenqi, Wu, Wei, Xia, Ruixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319929/
https://www.ncbi.nlm.nih.gov/pubmed/32606967
http://dx.doi.org/10.2147/CMAR.S253367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319929/
https://www.ncbi.nlm.nih.gov/pubmed/32606967
http://dx.doi.org/10.2147/CMAR.S253367

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