RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy

Receptor-interacting protein kinase-3 (RIPK3) is a multifunctional regulator of cell death and inflammation. RIPK3 controls cellular signalling through the formation of the domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, which is recognised to mediate renal fibrogenesis....

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Detalles Bibliográficos
Autores principales: Shi, Ying, Huang, Chunling, Zhao, Yongli, Cao, Qinghua, Yi, Hao, Chen, Xinming, Pollock, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319952/
https://www.ncbi.nlm.nih.gov/pubmed/32591618
http://dx.doi.org/10.1038/s41598-020-67054-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319952/
https://www.ncbi.nlm.nih.gov/pubmed/32591618
http://dx.doi.org/10.1038/s41598-020-67054-x

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