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A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment-resistant depression

The strategy of repeated ketamine in open-label and saline-control studies of treatment-resistant depression suggested greater antidepressant response beyond a single ketamine. However, consensus guideline stated the lack of evidence to support frequent ketamine administration. We compared the effic...

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Detalles Bibliográficos
Autores principales: Shiroma, Paulo R., Thuras, Paul, Wels, Joseph, Albott, C. Sophia, Erbes, Christopher, Tye, Susannah, Lim, Kelvin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319954/
https://www.ncbi.nlm.nih.gov/pubmed/32591498
http://dx.doi.org/10.1038/s41398-020-00897-0