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Focus on the spectra that matter by clustering of quantification data in shotgun proteomics
In shotgun proteomics, the analysis of label-free quantification experiments is typically limited by the identification rate and the noise level in the quantitative data. This generally causes a low sensitivity in differential expression analysis. Here, we propose a quantification-first approach for...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319958/ https://www.ncbi.nlm.nih.gov/pubmed/32591519 http://dx.doi.org/10.1038/s41467-020-17037-3 |