Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation

Protein arginine deiminase 4 (PAD4) facilitates the post-translational citrullination of the core histones H3 and H4. While the precise epigenetic function of this modification has not been resolved, it has been shown to associate with general chromatin decompaction and compete with arginine methyla...

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Detalles Bibliográficos
Autores principales: Zheng, Qingfei, Osunsade, Adewola, David, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319962/
https://www.ncbi.nlm.nih.gov/pubmed/32591537
http://dx.doi.org/10.1038/s41467-020-17066-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319962/
https://www.ncbi.nlm.nih.gov/pubmed/32591537
http://dx.doi.org/10.1038/s41467-020-17066-y

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