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Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
Protein arginine deiminase 4 (PAD4) facilitates the post-translational citrullination of the core histones H3 and H4. While the precise epigenetic function of this modification has not been resolved, it has been shown to associate with general chromatin decompaction and compete with arginine methyla...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319962/ https://www.ncbi.nlm.nih.gov/pubmed/32591537 http://dx.doi.org/10.1038/s41467-020-17066-y |